BDBM50306380 5-(4-(4-methyl-6-(trifluoromethyl)pyridin-2-yloxy)benzyl)thiazolidine-2,4-dione::CHEMBL601848

SMILES: Cc1cc(Oc2ccc(Cc3sc(=O)[nH]c3O)cc2)nc(c1)C(F)(F)F

InChI Key: InChIKey=LZRBFYPMZJECHR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306380 (5-(4-(4-methyl-6-(trifluoromethyl)pyridin-2-yloxy)...) Show SMILES Cc1cc(Oc2ccc(Cc3sc(=O)[nH]c3O)cc2)nc(c1)C(F)(F)F Show InChI InChI=1S/C17H13F3N2O3S/c1-9-6-13(17(18,19)20)21-14(7-9)25-11-4-2-10(3-5-11)8-12-15(23)22-16(24)26-12/h2-7,23H,8H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	688	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA				Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS
					More data for this Ligand-Target Pair