BDBM50306385 5-(4-(2-chloro-4-(trifluoromethyl)phenoxy)-2-methylbenzyl)thiazolidine-2,4-dione::CHEMBL600799

SMILES: Cc1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1Cc1sc(=O)[nH]c1O

InChI Key: InChIKey=RPDXULKKXYHOCI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306385 (5-(4-(2-chloro-4-(trifluoromethyl)phenoxy)-2-methy...) Show SMILES Cc1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1Cc1sc(=O)[nH]c1O Show InChI InChI=1S/C18H13ClF3NO3S/c1-9-6-12(4-2-10(9)7-15-16(24)23-17(25)27-15)26-14-5-3-11(8-13(14)19)18(20,21)22/h2-6,8,24H,7H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA				Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS
					More data for this Ligand-Target Pair