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BDBM50306392 5-((4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)naphthalen-1-yl)methyl)thiazolidine-2,4-dione::CHEMBL604317

SMILES: Oc1[nH]c(=O)sc1Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)c2ccccc12

InChI Key: InChIKey=SGVHBRVBNCFJLC-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306392   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50306392
PNG
(5-((4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy...)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)c2ccccc12
Show InChI InChI=1S/C20H12ClF3N2O3S/c21-14-8-11(20(22,23)24)9-25-18(14)29-15-6-5-10(12-3-1-2-4-13(12)15)7-16-17(27)26-19(28)30-16/h1-6,8-9,27H,7H2,(H,26,28)
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Similars
Article
PubMed
n/an/an/an/a 2.36E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA

Bioorg Med Chem Lett 20: 1298-301 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.052
BindingDB Entry DOI: 10.7270/Q2QC03KS
More data for this
Ligand-Target Pair