BDBM50306393 5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dione::CHEMBL598935

SMILES: Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(F)cc2)cc1

InChI Key: InChIKey=JTHIOMBKPKGALQ-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306393 (5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H12FNO3S/c17-11-3-7-13(8-4-11)21-12-5-1-10(2-6-12)9-14-15(19)18-16(20)22-14/h1-8,19H,9H2,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Partial agonist activity at human GPR40 expressed in CHO cells assessed as fatty acid-induced calcium mobilization by FLIPR assay				Eur J Med Chem 109: 157-72 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2JMM
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306393 (5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H12FNO3S/c17-11-3-7-13(8-4-11)21-12-5-1-10(2-6-12)9-14-15(19)18-16(20)22-14/h1-8,19H,9H2,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	474	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 3390-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.114 BindingDB Entry DOI: 10.7270/Q2KP82GX
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306393 (5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H12FNO3S/c17-11-3-7-13(8-4-11)21-12-5-1-10(2-6-12)9-14-15(19)18-16(20)22-14/h1-8,19H,9H2,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA				Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS
					More data for this Ligand-Target Pair