BDBM50306396 3-(4-(2,4-dichlorophenoxy)benzyl)pyrrolidine-2,5-dione::CHEMBL589992

SMILES: Clc1ccc(Oc2ccc(CC3CC(=O)NC3=O)cc2)c(Cl)c1

InChI Key: InChIKey=RGFNPCCTJCQSLV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50306396 (3-(4-(2,4-dichlorophenoxy)benzyl)pyrrolidine-2,5-d...) Show SMILES Clc1ccc(Oc2ccc(CC3CC(=O)NC3=O)cc2)c(Cl)c1 Show InChI InChI=1S/C17H13Cl2NO3/c18-12-3-6-15(14(19)9-12)23-13-4-1-10(2-5-13)7-11-8-16(21)20-17(11)22/h1-6,9,11H,7-8H2,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.45E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA				Bioorg Med Chem Lett 20: 1298-301 (2010) Article DOI: 10.1016/j.bmcl.2009.10.052 BindingDB Entry DOI: 10.7270/Q2QC03KS
					More data for this Ligand-Target Pair