BDBM50306413 2-Phenyl-piperidine-1-carboxylic acid adamantan-2-ylamide::CHEMBL598039

SMILES:

InChI Key: InChIKey=GIGLBOSGXWTEJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306413 (2-Phenyl-piperidine-1-carboxylic acid adamantan-2-...) Show SMILES Show InChI InChI=1S/C22H30N2O/c25-22(23-21-18-11-15-10-16(13-18)14-19(21)12-15)24-9-5-4-8-20(24)17-6-2-1-3-7-17/h1-3,6-7,15-16,18-21H,4-5,8-14H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol by SPA				Bioorg Med Chem Lett 20: 881-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.082 BindingDB Entry DOI: 10.7270/Q2KK9BWZ
					More data for this Ligand-Target Pair