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SMILES: CCc1cccc2c(c[nH]c12)C1=CCN(CCc2coc3ccccc23)CC1

InChI Key: InChIKey=RPSQOMYJVGUUOS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306481   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50306481
PNG
(3-(1-(2-(benzofuran-3-yl)ethyl)-1,2,3,6-tetrahydro...)
Show SMILES CCc1cccc2c(c[nH]c12)C1=CCN(CCc2coc3ccccc23)CC1 |t:13|
Show InChI InChI=1S/C25H26N2O/c1-2-18-6-5-8-22-23(16-26-25(18)22)19-10-13-27(14-11-19)15-12-20-17-28-24-9-4-3-7-21(20)24/h3-10,16-17,26H,2,11-15H2,1H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 156n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from 5-HT transporter in rat frontal cortical synaptosomes

Bioorg Med Chem Lett 20: 824-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.093
BindingDB Entry DOI: 10.7270/Q2B56JVJ
More data for this
Ligand-Target Pair