BDBM50306670 CHEMBL599871::[(4-Bromo-phenyl)-p-tolyl-ketone]thiosemicarbazone

SMILES: Cc1ccc(cc1)C(=NNC(N)=S)c1ccc(Br)cc1

InChI Key: InChIKey=VFDNQCFIHZOSJF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin B (Homo sapiens (Human))	BDBM50306670 (CHEMBL599871 | [(4-Bromo-phenyl)-p-tolyl-ketone]th...) Show SMILES Cc1ccc(cc1)C(=NNC(N)=S)c1ccc(Br)cc1 |w:8.9| Show InChI InChI=1S/C15H14BrN3S/c1-10-2-4-11(5-3-10)14(18-19-15(17)20)12-6-8-13(16)9-7-12/h2-9H,1H3,(H3,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin B				Bioorg Med Chem Lett 20: 1415-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.090 BindingDB Entry DOI: 10.7270/Q2NG4QQZ
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50306670 (CHEMBL599871 | [(4-Bromo-phenyl)-p-tolyl-ketone]th...) Show SMILES Cc1ccc(cc1)C(=NNC(N)=S)c1ccc(Br)cc1 |w:8.9| Show InChI InChI=1S/C15H14BrN3S/c1-10-2-4-11(5-3-10)14(18-19-15(17)20)12-6-8-13(16)9-7-12/h2-9H,1H3,(H3,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				Bioorg Med Chem Lett 20: 1415-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.090 BindingDB Entry DOI: 10.7270/Q2NG4QQZ
					More data for this Ligand-Target Pair