BDBM50306821 CHEMBL602889::N-(Cyclopropylmethyl)-N-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)quinoline-8-sulfonamid

SMILES: Fc1ccc(cc1)N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1

InChI Key: InChIKey=VFUQKLHANIZIQH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50306821 (CHEMBL602889 | N-(Cyclopropylmethyl)-N-(3-(4-(4-fl...) Show SMILES Fc1ccc(cc1)N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1 Show InChI InChI=1S/C26H31FN4O2S/c27-23-9-11-24(12-10-23)30-18-16-29(17-19-30)14-3-15-31(20-21-7-8-21)34(32,33)25-6-1-4-22-5-2-13-28-26(22)25/h1-2,4-6,9-13,21H,3,7-8,14-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50306821 (CHEMBL602889 | N-(Cyclopropylmethyl)-N-(3-(4-(4-fl...) Show SMILES Fc1ccc(cc1)N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1 Show InChI InChI=1S/C26H31FN4O2S/c27-23-9-11-24(12-10-23)30-18-16-29(17-19-30)14-3-15-31(20-21-7-8-21)34(32,33)25-6-1-4-22-5-2-13-28-26(22)25/h1-2,4-6,9-13,21H,3,7-8,14-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35.3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50306821 (CHEMBL602889 | N-(Cyclopropylmethyl)-N-(3-(4-(4-fl...) Show SMILES Fc1ccc(cc1)N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1 Show InChI InChI=1S/C26H31FN4O2S/c27-23-9-11-24(12-10-23)30-18-16-29(17-19-30)14-3-15-31(20-21-7-8-21)34(32,33)25-6-1-4-22-5-2-13-28-26(22)25/h1-2,4-6,9-13,21H,3,7-8,14-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair