BDBM50306822 CHEMBL603092::N-(4-(4-Phenylpiperazin-1-yl)butan-2-yl)naphthalene-2-sulfonamide

SMILES: CC(CCN1CCN(CC1)c1ccccc1)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=MFBRVGWZBCQSSV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50306822 (CHEMBL603092 | N-(4-(4-Phenylpiperazin-1-yl)butan-...) Show SMILES CC(CCN1CCN(CC1)c1ccccc1)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-20(13-14-26-15-17-27(18-16-26)23-9-3-2-4-10-23)25-30(28,29)24-12-11-21-7-5-6-8-22(21)19-24/h2-12,19-20,25H,13-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50306822 (CHEMBL603092 | N-(4-(4-Phenylpiperazin-1-yl)butan-...) Show SMILES CC(CCN1CCN(CC1)c1ccccc1)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-20(13-14-26-15-17-27(18-16-26)23-9-3-2-4-10-23)25-30(28,29)24-12-11-21-7-5-6-8-22(21)19-24/h2-12,19-20,25H,13-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	657	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50306822 (CHEMBL603092 | N-(4-(4-Phenylpiperazin-1-yl)butan-...) Show SMILES CC(CCN1CCN(CC1)c1ccccc1)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-20(13-14-26-15-17-27(18-16-26)23-9-3-2-4-10-23)25-30(28,29)24-12-11-21-7-5-6-8-22(21)19-24/h2-12,19-20,25H,13-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair