BDBM50306835 CHEMBL600210::N-(Cyclohexylmethyl)-N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)naphthalene-2-sulfonamide

SMILES: COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2ccc3ccccc3c2)CC1

InChI Key: InChIKey=DVKVDTQSWBEYCJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50306835 (CHEMBL600210 | N-(Cyclohexylmethyl)-N-(3-(4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C31H41N3O3S/c1-37-31-15-8-7-14-30(31)33-22-20-32(21-23-33)18-9-19-34(25-26-10-3-2-4-11-26)38(35,36)29-17-16-27-12-5-6-13-28(27)24-29/h5-8,12-17,24,26H,2-4,9-11,18-23,25H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50306835 (CHEMBL600210 | N-(Cyclohexylmethyl)-N-(3-(4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C31H41N3O3S/c1-37-31-15-8-7-14-30(31)33-22-20-32(21-23-33)18-9-19-34(25-26-10-3-2-4-11-26)38(35,36)29-17-16-27-12-5-6-13-28(27)24-29/h5-8,12-17,24,26H,2-4,9-11,18-23,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50306835 (CHEMBL600210 | N-(Cyclohexylmethyl)-N-(3-(4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C31H41N3O3S/c1-37-31-15-8-7-14-30(31)33-22-20-32(21-23-33)18-9-19-34(25-26-10-3-2-4-11-26)38(35,36)29-17-16-27-12-5-6-13-28(27)24-29/h5-8,12-17,24,26H,2-4,9-11,18-23,25H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair