BDBM50306844 CHEMBL601458::N-(Cyclopropylmethyl)-N-(3-(4-phenylpiperazin-1-yl)-propyl)-4-(trifluoromethyl)benzenesulfonamide

SMILES: FC(F)(F)c1ccc(cc1)S(=O)(=O)N(CCCN1CCN(CC1)c1ccccc1)CC1CC1

InChI Key: InChIKey=KCKBXDZTJJWHFS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50306844 (CHEMBL601458 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...) Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N(CCCN1CCN(CC1)c1ccccc1)CC1CC1 Show InChI InChI=1S/C24H30F3N3O2S/c25-24(26,27)21-9-11-23(12-10-21)33(31,32)30(19-20-7-8-20)14-4-13-28-15-17-29(18-16-28)22-5-2-1-3-6-22/h1-3,5-6,9-12,20H,4,7-8,13-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	565	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50306844 (CHEMBL601458 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...) Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N(CCCN1CCN(CC1)c1ccccc1)CC1CC1 Show InChI InChI=1S/C24H30F3N3O2S/c25-24(26,27)21-9-11-23(12-10-21)33(31,32)30(19-20-7-8-20)14-4-13-28-15-17-29(18-16-28)22-5-2-1-3-6-22/h1-3,5-6,9-12,20H,4,7-8,13-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70.8	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50306844 (CHEMBL601458 | N-(Cyclopropylmethyl)-N-(3-(4-pheny...) Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N(CCCN1CCN(CC1)c1ccccc1)CC1CC1 Show InChI InChI=1S/C24H30F3N3O2S/c25-24(26,27)21-9-11-23(12-10-21)33(31,32)30(19-20-7-8-20)14-4-13-28-15-17-29(18-16-28)22-5-2-1-3-6-22/h1-3,5-6,9-12,20H,4,7-8,13-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells				Bioorg Med Chem 18: 1665-75 (2010) Article DOI: 10.1016/j.bmc.2009.12.067 BindingDB Entry DOI: 10.7270/Q2R78F99
					More data for this Ligand-Target Pair