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SMILES: CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccncc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=WSWFVWGYTSBUQW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily A member 5


(Homo sapiens (Human))		BDBM50306894
PNG
((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccncc1)c1ccc(Cl)c(Cl)c1 |t:1|
Show InChI InChI=1S/C23H21Cl2N5O/c1-14-21(23(31)29-12-2-3-19(29)15-6-9-26-10-7-15)22(30-20(28-14)8-11-27-30)16-4-5-17(24)18(25)13-16/h4-11,13,19,21-22H,2-3,12H2,1H3
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Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Kv1.5 channel expressed in mouse L929 cells

Bioorg Med Chem Lett 20: 1436-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.085
BindingDB Entry DOI: 10.7270/Q2MG7PM1
More data for this
Ligand-Target Pair