Found 3 hits for monomerid = 50307271 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307271
((2,5-Dimethyl-2H-pyrazol-3-yl)-carbamic acid 2-(2-...)Show SMILES Cc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C23H23N5O3S/c1-14-11-21(28(2)27-14)26-23(29)30-13-18(15-7-4-3-5-8-15)31-17-9-6-10-19-16(17)12-20(32-19)22(24)25/h3-12,18H,13H2,1-2H3,(H3,24,25)(H,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307271
((2,5-Dimethyl-2H-pyrazol-3-yl)-carbamic acid 2-(2-...)Show SMILES Cc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C23H23N5O3S/c1-14-11-21(28(2)27-14)26-23(29)30-13-18(15-7-4-3-5-8-15)31-17-9-6-10-19-16(17)12-20(32-19)22(24)25/h3-12,18H,13H2,1-2H3,(H3,24,25)(H,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307271
((2,5-Dimethyl-2H-pyrazol-3-yl)-carbamic acid 2-(2-...)Show SMILES Cc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C23H23N5O3S/c1-14-11-21(28(2)27-14)26-23(29)30-13-18(15-7-4-3-5-8-15)31-17-9-6-10-19-16(17)12-20(32-19)22(24)25/h3-12,18H,13H2,1-2H3,(H3,24,25)(H,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |