BDBM50307911 4-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbonitrile::CHEMBL608153

SMILES: N#Cc1cc(Cn2cncn2)ccc1-c1ccccc1

InChI Key: InChIKey=XXLOSISKPNPYGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50307911 (4-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbon...) Show SMILES N#Cc1cc(Cn2cncn2)ccc1-c1ccccc1 Show InChI InChI=1S/C16H12N4/c17-9-15-8-13(10-20-12-18-11-19-20)6-7-16(15)14-4-2-1-3-5-14/h1-8,11-12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of aromatse in human JEG3 cells by scintillation spectrometry				J Med Chem 53: 2155-70 (2010) Article DOI: 10.1021/jm901705h BindingDB Entry DOI: 10.7270/Q2959JGF
					More data for this Ligand-Target Pair