null

SMILES: CCOc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1

InChI Key: InChIKey=LXRFOXKXUGKQGV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308204 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-7-5-13(6-8-14)22-19-21-11-12-10-16(25)23-15-4-3-9-20-18(15)17(12)24-19/h3-9,11H,2,10H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308204 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-7-5-13(6-8-14)22-19-21-11-12-10-16(25)23-15-4-3-9-20-18(15)17(12)24-19/h3-9,11H,2,10H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50308204 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-7-5-13(6-8-14)22-19-21-11-12-10-16(25)23-15-4-3-9-20-18(15)17(12)24-19/h3-9,11H,2,10H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of INSR assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair