BDBM50308441 (2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL602524::US8541380, 29

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2nnc(s2)-c2ccc(Cl)cc2)c1

InChI Key: InChIKey=YZIZVZHMSVHPHJ-PKOFMYQESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50308441 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(4-chlorophenyl...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2nnc(s2)-c2ccc(Cl)cc2)c1 |r| Show InChI InChI=1S/C21H20Cl2N2O5S/c22-13-4-1-10(2-5-13)21-25-24-16(31-21)8-12-7-11(3-6-14(12)23)20-19(29)18(28)17(27)15(9-26)30-20/h1-7,15,17-20,26-29H,8-9H2/t15-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant SGLT2 expressed in CHO cells by liquid scintillation counting				Bioorg Med Chem 18: 2178-94 (2010) Article DOI: 10.1016/j.bmc.2010.01.073 BindingDB Entry DOI: 10.7270/Q2MG7QF6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50308441 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(4-chlorophenyl...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2nnc(s2)-c2ccc(Cl)cc2)c1 |r| Show InChI InChI=1S/C21H20Cl2N2O5S/c22-13-4-1-10(2-5-13)21-25-24-16(31-21)8-12-7-11(3-6-14(12)23)20-19(29)18(28)17(27)15(9-26)30-20/h1-7,15,17-20,26-29H,8-9H2/t15-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation US Patent					Assay Description Inhibition assay using hSGLT2.				US Patent US8541380 (2013) BindingDB Entry DOI: 10.7270/Q2T43RQ3
					More data for this Ligand-Target Pair