BDBM50308453 (2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(5-methylfuran-2-yl)-1,3,4-thiadiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL590991::US8541380, 2

SMILES: Cc1ccc(o1)-c1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1

InChI Key: InChIKey=ZSCMYSGDPGMPFI-FTWQHDNSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50308453 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(5-methylfuran-...) Show SMILES Cc1ccc(o1)-c1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1 |r| Show InChI InChI=1S/C20H21ClN2O6S/c1-9-2-5-13(28-9)20-23-22-15(30-20)7-11-6-10(3-4-12(11)21)19-18(27)17(26)16(25)14(8-24)29-19/h2-6,14,16-19,24-27H,7-8H2,1H3/t14-,16-,17+,18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58.3	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant SGLT2 expressed in CHO cells by liquid scintillation counting				Bioorg Med Chem 18: 2178-94 (2010) Article DOI: 10.1016/j.bmc.2010.01.073 BindingDB Entry DOI: 10.7270/Q2MG7QF6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50308453 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(5-methylfuran-...) Show SMILES Cc1ccc(o1)-c1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1 |r| Show InChI InChI=1S/C20H21ClN2O6S/c1-9-2-5-13(28-9)20-23-22-15(30-20)7-11-6-10(3-4-12(11)21)19-18(27)17(26)16(25)14(8-24)29-19/h2-6,14,16-19,24-27H,7-8H2,1H3/t14-,16-,17+,18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58.3	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation US Patent					Assay Description Inhibition assay using hSGLT2.				US Patent US8541380 (2013) BindingDB Entry DOI: 10.7270/Q2T43RQ3
					More data for this Ligand-Target Pair