BDBM50308535 CHEMBL601712::methyl (14E)-14-ethylidene-6-methoxy-2-methyl-19-[(propanoyloxy)methyl]-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate

SMILES: CCC(=O)OC[C@]1([C@H]2C[C@@H]3N(C\C2=C\C)[C@@H]2C[C@]11c4cc(OC)ccc4N(C)[C@]31O2)C(=O)OC

InChI Key: InChIKey=QFMJKUUFXXEIGZ-ANTLQJRQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50308535 (CHEMBL601712 | methyl (14E)-14-ethylidene-6-methox...) Show SMILES CCC(=O)OC[C@]1([C@H]2C[C@@H]3N(C\C2=C\C)[C@@H]2C[C@]11c4cc(OC)ccc4N(C)[C@]31O2)C(=O)OC |r| Show InChI InChI=1S/C26H32N2O6/c1-6-15-13-28-20-11-17(15)24(23(30)32-5,14-33-22(29)7-2)25-12-21(28)34-26(20,25)27(3)19-9-8-16(31-4)10-18(19)25/h6,8-10,17,20-21H,7,11-14H2,1-5H3/b15-6-/t17-,20-,21-,24-,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoshi University Curated by ChEMBL					Assay Description Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation...				Bioorg Med Chem 18: 2152-8 (2010) Article DOI: 10.1016/j.bmc.2010.01.077 BindingDB Entry DOI: 10.7270/Q2HD7VSQ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50308535 (CHEMBL601712 | methyl (14E)-14-ethylidene-6-methox...) Show SMILES CCC(=O)OC[C@]1([C@H]2C[C@@H]3N(C\C2=C\C)[C@@H]2C[C@]11c4cc(OC)ccc4N(C)[C@]31O2)C(=O)OC |r| Show InChI InChI=1S/C26H32N2O6/c1-6-15-13-28-20-11-17(15)24(23(30)32-5,14-33-22(29)7-2)25-12-21(28)34-26(20,25)27(3)19-9-8-16(31-4)10-18(19)25/h6,8-10,17,20-21H,7,11-14H2,1-5H3/b15-6-/t17-,20-,21-,24-,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoshi University Curated by ChEMBL					Assay Description Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation...				Bioorg Med Chem 18: 2152-8 (2010) Article DOI: 10.1016/j.bmc.2010.01.077 BindingDB Entry DOI: 10.7270/Q2HD7VSQ
					More data for this Ligand-Target Pair