BDBM50309421 2-(4-(4-phenoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid::CHEMBL596712

SMILES: OC(=O)Cc1sc(Nc2ccccc2)nc1-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=DFCMQNJBQNIEHU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309421 (2-(4-(4-phenoxyphenyl)-2-(phenylamino)thiazol-5-yl...) Show SMILES OC(=O)Cc1sc(Nc2ccccc2)nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H18N2O3S/c26-21(27)15-20-22(25-23(29-20)24-17-7-3-1-4-8-17)16-11-13-19(14-12-16)28-18-9-5-2-6-10-18/h1-14H,15H2,(H,24,25)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cells				Bioorg Med Chem Lett 20: 1177-80 (2010) Article DOI: 10.1016/j.bmcl.2009.12.008 BindingDB Entry DOI: 10.7270/Q25T3KMP
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309421 (2-(4-(4-phenoxyphenyl)-2-(phenylamino)thiazol-5-yl...) Show SMILES OC(=O)Cc1sc(Nc2ccccc2)nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H18N2O3S/c26-21(27)15-20-22(25-23(29-20)24-17-7-3-1-4-8-17)16-11-13-19(14-12-16)28-18-9-5-2-6-10-18/h1-14H,15H2,(H,24,25)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...				Bioorg Med Chem Lett 20: 1177-80 (2010) Article DOI: 10.1016/j.bmcl.2009.12.008 BindingDB Entry DOI: 10.7270/Q25T3KMP
					More data for this Ligand-Target Pair