BDBM50310358 3-(2'-Methylphenyl)-1H-naphtho[2,1-b]pyran-1-one::CHEMBL611384

SMILES: Cc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1

InChI Key: InChIKey=HTQOUKGHDBLEQZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310358 (3-(2'-Methylphenyl)-1H-naphtho[2,1-b]pyran-1-one |...) Show SMILES Cc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI InChI=1S/C20H14O2/c1-13-6-2-4-8-15(13)19-12-17(21)20-16-9-5-3-7-14(16)10-11-18(20)22-19/h2-12H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at AhR in human MCF-7 cells assessed as increase of CYP1A1-dependent 7-ethoxyresorufin O-deethylase activity				J Med Chem 54: 1539-54 (2011) Article DOI: 10.1021/jm101356p BindingDB Entry DOI: 10.7270/Q27S7P30
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50310358 (3-(2'-Methylphenyl)-1H-naphtho[2,1-b]pyran-1-one |...) Show SMILES Cc1ccccc1-c1cc(=O)c2c(ccc3ccccc23)o1 Show InChI InChI=1S/C20H14O2/c1-13-6-2-4-8-15(13)19-12-17(21)20-16-9-5-3-7-14(16)10-11-18(20)22-19/h2-12H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay				Bioorg Med Chem 18: 1194-203 (2010) Article DOI: 10.1016/j.bmc.2009.12.036 BindingDB Entry DOI: 10.7270/Q2GX4BNF
					More data for this Ligand-Target Pair