BDBM50310617 CHEMBL1078926::N-(3-(1H-benzo[d]imidazol-2-ylamino)benzyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: C(Nc1ncnc2ccsc12)c1cccc(Nc2nc3ccccc3[nH]2)c1

InChI Key: InChIKey=RDXHPHYQWFZWFU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310617   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310617 (CHEMBL1078926 | N-(3-(1H-benzo[d]imidazol-2-ylamin...) Show SMILES C(Nc1ncnc2ccsc12)c1cccc(Nc2nc3ccccc3[nH]2)c1 Show InChI InChI=1S/C20H16N6S/c1-2-7-16-15(6-1)25-20(26-16)24-14-5-3-4-13(10-14)11-21-19-18-17(8-9-27-18)22-12-23-19/h1-10,12H,11H2,(H,21,22,23)(H2,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair