BDBM50310670 (R)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)-3-(ethylthio)propanamide::CHEMBL1082054

SMILES: CCSC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N

InChI Key: InChIKey=DULUBSMWYBEFLC-JSGCOSHPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50310670 ((R)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...) Show SMILES CCSC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C#N |r| Show InChI InChI=1S/C16H20N4OS/c1-2-22-10-14(18)16(21)20-12(8-17)7-11-9-19-15-6-4-3-5-13(11)15/h3-6,9,12,14,19H,2,7,10,18H2,1H3,(H,20,21)/t12-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair