BDBM50310695 (S)-N-((S)-1-cyano-2-(4-fluorophenyl)ethyl)pyrrolidine-2-carboxamide::CHEMBL1080251

SMILES: Fc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2)C#N)cc1

InChI Key: InChIKey=RMLPOSXGONZSBV-STQMWFEESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50310695 ((S)-N-((S)-1-cyano-2-(4-fluorophenyl)ethyl)pyrroli...) Show SMILES Fc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2)C#N)cc1 |r| Show InChI InChI=1S/C14H16FN3O/c15-11-5-3-10(4-6-11)8-12(9-16)18-14(19)13-2-1-7-17-13/h3-6,12-13,17H,1-2,7-8H2,(H,18,19)/t12-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair