BDBM50310696 (2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthio)pyrrolidine-2-carboxamide::CHEMBL1081149

SMILES: CS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N

InChI Key: InChIKey=INHIPGIGWGRJGP-IHRRRGAJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50310696 ((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthi...) Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccccc1)C#N |r| Show InChI InChI=1S/C15H19N3OS/c1-20-13-8-14(17-10-13)15(19)18-12(9-16)7-11-5-3-2-4-6-11/h2-6,12-14,17H,7-8,10H2,1H3,(H,18,19)/t12-,13-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair