BDBM50310702 (2S,4S)-N-(1-cyanocyclopropyl)-4-(methylthio)pyrrolidine-2-carboxamide::CHEMBL1078067

SMILES: CS[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1)C#N

InChI Key: InChIKey=XHSDBDAODUWXLQ-YUMQZZPRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50310702 ((2S,4S)-N-(1-cyanocyclopropyl)-4-(methylthio)pyrro...) Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C10H15N3OS/c1-15-7-4-8(12-5-7)9(14)13-10(6-11)2-3-10/h7-8,12H,2-5H2,1H3,(H,13,14)/t7-,8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair