BDBM50311367 CHEMBL1079877::N-(3-phenylamino-4-pyridinyl)methanesulfonamide

SMILES: CS(=O)(=O)Nc1ccncc1Nc1ccccc1

InChI Key: InChIKey=QOJPQADRTOBBQV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50311367 (CHEMBL1079877 | N-(3-phenylamino-4-pyridinyl)metha...) Show SMILES CS(=O)(=O)Nc1ccncc1Nc1ccccc1 Show InChI InChI=1S/C12H13N3O2S/c1-18(16,17)15-11-7-8-13-9-12(11)14-10-5-3-2-4-6-10/h2-9,14H,1H3,(H,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay				J Med Chem 52: 5864-71 (2009) Article DOI: 10.1021/jm900702b BindingDB Entry DOI: 10.7270/Q2CV4JQ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50311367 (CHEMBL1079877 | N-(3-phenylamino-4-pyridinyl)metha...) Show SMILES CS(=O)(=O)Nc1ccncc1Nc1ccccc1 Show InChI InChI=1S/C12H13N3O2S/c1-18(16,17)15-11-7-8-13-9-12(11)14-10-5-3-2-4-6-10/h2-9,14H,1H3,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Inhibition of COX2 in LPS-stimulated human whole blood assessed as PGE2 production by enzyme immunoassay				J Med Chem 52: 5864-71 (2009) Article DOI: 10.1021/jm900702b BindingDB Entry DOI: 10.7270/Q2CV4JQ6
					More data for this Ligand-Target Pair