null

SMILES: Cc1ccc(Nc2cnccc2NS(C)(=O)=O)cc1

InChI Key: InChIKey=QUVHDJSZHHKWSL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50311375 (CHEMBL1078376 | N-[3-(4-methylphenylamino)-4-pyrid...) Show SMILES Cc1ccc(Nc2cnccc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H15N3O2S/c1-10-3-5-11(6-4-10)15-13-9-14-8-7-12(13)16-19(2,17)18/h3-9,15H,1-2H3,(H,14,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay				J Med Chem 52: 5864-71 (2009) Article DOI: 10.1021/jm900702b BindingDB Entry DOI: 10.7270/Q2CV4JQ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50311375 (CHEMBL1078376 | N-[3-(4-methylphenylamino)-4-pyrid...) Show SMILES Cc1ccc(Nc2cnccc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C13H15N3O2S/c1-10-3-5-11(6-4-10)15-13-9-14-8-7-12(13)16-19(2,17)18/h3-9,15H,1-2H3,(H,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Inhibition of COX2 in LPS-stimulated human whole blood assessed as PGE2 production by enzyme immunoassay				J Med Chem 52: 5864-71 (2009) Article DOI: 10.1021/jm900702b BindingDB Entry DOI: 10.7270/Q2CV4JQ6
					More data for this Ligand-Target Pair