BDBM50312481 2-(4-((4-(2-Morpholinopyrimidin-5-yl)-5-(4-(trifluoromethoxy)-phenyl)oxazol-2-yl)methoxy)-2-methylphenoxy)acetic Acid::CHEMBL1075895

SMILES: Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2cnc(nc2)N2CCOCC2)ccc1OCC(O)=O

InChI Key: InChIKey=ARDLYEQBIROAPF-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312481 (2-(4-((4-(2-Morpholinopyrimidin-5-yl)-5-(4-(triflu...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2cnc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C28H25F3N4O7/c1-17-12-21(6-7-22(17)40-16-24(36)37)39-15-23-34-25(19-13-32-27(33-14-19)35-8-10-38-11-9-35)26(41-23)18-2-4-20(5-3-18)42-28(29,30)31/h2-7,12-14H,8-11,15-16H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312481 (2-(4-((4-(2-Morpholinopyrimidin-5-yl)-5-(4-(triflu...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2cnc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C28H25F3N4O7/c1-17-12-21(6-7-22(17)40-16-24(36)37)39-15-23-34-25(19-13-32-27(33-14-19)35-8-10-38-11-9-35)26(41-23)18-2-4-20(5-3-18)42-28(29,30)31/h2-7,12-14H,8-11,15-16H2,1H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312481 (2-(4-((4-(2-Morpholinopyrimidin-5-yl)-5-(4-(triflu...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2cnc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C28H25F3N4O7/c1-17-12-21(6-7-22(17)40-16-24(36)37)39-15-23-34-25(19-13-32-27(33-14-19)35-8-10-38-11-9-35)26(41-23)18-2-4-20(5-3-18)42-28(29,30)31/h2-7,12-14H,8-11,15-16H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair