BDBM50313291 (1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1081452

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@H]1CN2

InChI Key: InChIKey=NLRPQPISQZRZTP-STQMWFEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50313291 ((1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabi...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@H]1CN2 |r,THB:10:13:18.19:16| Show InChI InChI=1S/C15H22N2O2S/c1-15(2,3)11-4-6-14(7-5-11)20(18,19)17-10-12-8-13(17)9-16-12/h4-7,12-13,16H,8-10H2,1-3H3/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50313291 ((1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabi...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@H]1CN2 |r,THB:10:13:18.19:16| Show InChI InChI=1S/C15H22N2O2S/c1-15(2,3)11-4-6-14(7-5-11)20(18,19)17-10-12-8-13(17)9-16-12/h4-7,12-13,16H,8-10H2,1-3H3/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair