BDBM50313315 6-(tert-butylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide::CHEMBL1081081

SMILES: Cc1cc(O)ccc1NC(=O)c1cc(NC(C)(C)C)ncn1

InChI Key: InChIKey=BIGFIHWLLJWDAA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50313315 (6-(tert-butylamino)-N-(4-hydroxy-2-methylphenyl)py...) Show SMILES Cc1cc(O)ccc1NC(=O)c1cc(NC(C)(C)C)ncn1 Show InChI InChI=1S/C16H20N4O2/c1-10-7-11(21)5-6-12(10)19-15(22)13-8-14(18-9-17-13)20-16(2,3)4/h5-9,21H,1-4H3,(H,19,22)(H,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assay				Bioorg Med Chem Lett 20: 1516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.102 BindingDB Entry DOI: 10.7270/Q2J38SQK
					More data for this Ligand-Target Pair