BDBM50313755 1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-phenyl-4,5-dihydro-1H pyrazole::CHEMBL1082880

SMILES: COc1cc(cc(OC)c1OC)C1=NN(C)C(C1)c1ccccc1

InChI Key: InChIKey=LPGZJRNIFDEZLK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50313755 (1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-phenyl-4,...) Show SMILES COc1cc(cc(OC)c1OC)C1=NN(C)C(C1)c1ccccc1 |t:13| Show InChI InChI=1S/C19H22N2O3/c1-21-16(13-8-6-5-7-9-13)12-15(20-21)14-10-17(22-2)19(24-4)18(11-14)23-3/h5-11,16H,12H2,1-4H3	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Calabria Curated by ChEMBL					Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis				Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4
					More data for this Ligand-Target Pair