BDBM50313758 1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-(3''-hydroxy-4''-methoxyphenyl)-4,5-dihydro-1H pyrazole::CHEMBL1082883
SMILES: COc1ccc(cc1O)C1CC(=NN1C)c1cc(OC)c(OC)c(OC)c1
InChI Key: InChIKey=LGJLFHYLMGCVHP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50313758 (1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-(3''-hydr...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calabria Curated by ChEMBL | Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis | Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4 | |||||||||||
More data for this Ligand-Target Pair |