BDBM50313763 1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-(3''-fluoro-4''-methoxyphenyl)-4,5-dihydro-1H pyrazole::CHEMBL1083525

SMILES: COc1ccc(cc1F)C1CC(=NN1C)c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=HSKCETLIRMHPBS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50313763 (1-methyl-3-(3',4',5'-trimethoxyphenyl)-5-(3''-fluo...) Show SMILES COc1ccc(cc1F)C1CC(=NN1C)c1cc(OC)c(OC)c(OC)c1 |c:12| Show InChI InChI=1S/C20H23FN2O4/c1-23-16(12-6-7-17(24-2)14(21)8-12)11-15(22-23)13-9-18(25-3)20(27-5)19(10-13)26-4/h6-10,16H,11H2,1-5H3	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Calabria Curated by ChEMBL					Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis				Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4
					More data for this Ligand-Target Pair