BDBM50313854 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-2-methylpyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL1084413

SMILES: COc1ccc(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)c(C)n1

InChI Key: InChIKey=NZIABYFTQSXPOJ-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50313854 ((R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-2...) Show SMILES COc1ccc(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)c(C)n1 |r| Show InChI InChI=1S/C16H19ClN4O2/c1-9-12(6-7-14(18-9)23-3)19-15-16(22)21(8-13(17)20-15)10(2)11-4-5-11/h6-8,10-11H,4-5H2,1-3H3,(H,19,20)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma counting				Bioorg Med Chem Lett 20: 1890-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.129 BindingDB Entry DOI: 10.7270/Q29G5MZ4
					More data for this Ligand-Target Pair