BDBM50314041 (4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S,43S,46S,49S,52S,55S,58S,61S,67S)-4-((8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-1-((S)-2-((S)-1-((S)-1-(2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-1-amino-3-hydroxy-1-oxopropan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)pyrrolidine-1-carbonyl)pyrrolidin-1-yl)-1-oxopropan-2-ylamino)-2-oxoethylamino)-3-hydroxy-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-11-(4-((R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro::CHEMBL1092708

SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

InChI Key: InChIKey=GCHBNWIZQJCAGZ-QSACVTEBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Rattus norvegicus)	BDBM50314041 ((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37S,40S...) Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C208H319N49O63S/c1-19-108(10)169(199(313)237-135(60-67-166(282)283)185(299)241-141(86-116-91-219-126-42-27-26-41-120(116)126)189(303)239-137(81-104(2)3)187(301)229-128(44-29-31-74-217-156(268)62-50-109(11)122-53-54-123-121-52-51-117-87-119(265)68-71-207(117,16)124(121)69-72-208(122,123)17)180(294)242-142(89-155(212)267)176(290)222-93-157(269)220-97-161(273)254-76-33-46-149(254)195(309)247-146(100-260)194(308)246-145(99-259)177(291)224-94-158(270)226-111(13)202(316)256-78-35-48-151(256)204(318)257-79-36-49-152(257)203(317)255-77-34-47-150(255)196(310)245-144(98-258)172(213)286)252-190(304)139(84-114-37-22-20-23-38-114)240-188(302)138(82-105(4)5)238-181(295)129(45-32-75-218-206(214)215)236-198(312)168(107(8)9)251-173(287)110(12)227-178(292)132(57-64-163(276)277)232-183(297)133(58-65-164(278)279)233-184(298)134(59-66-165(280)281)234-186(300)136(70-80-321-18)235-182(296)131(55-61-154(211)266)231-179(293)127(43-28-30-73-209)230-192(306)147(101-261)248-197(311)153(83-106(6)7)320-205(319)143(90-167(284)285)244-193(307)148(102-262)249-201(315)171(113(15)264)253-191(305)140(85-115-39-24-21-25-40-115)243-200(314)170(112(14)263)250-160(272)96-223-175(289)130(56-63-162(274)275)228-159(271)95-221-174(288)125(210)88-118-92-216-103-225-118/h20-27,37-42,91-92,103-113,117,119,121-125,127-153,168-171,219,258-265H,19,28-36,43-90,93-102,209-210H2,1-18H3,(H2,211,266)(H2,212,267)(H2,213,286)(H,216,225)(H,217,268)(H,220,269)(H,221,288)(H,222,290)(H,223,289)(H,224,291)(H,226,270)(H,227,292)(H,228,271)(H,229,301)(H,230,306)(H,231,293)(H,232,297)(H,233,298)(H,234,300)(H,235,296)(H,236,312)(H,237,313)(H,238,295)(H,239,303)(H,240,302)(H,241,299)(H,242,294)(H,243,314)(H,244,307)(H,245,310)(H,246,308)(H,247,309)(H,248,311)(H,249,315)(H,250,272)(H,251,287)(H,252,304)(H,253,305)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H4,214,215,218)/t108-,109+,110-,111-,112+,113+,117+,119+,121-,122+,123-,124-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,168-,169-,170-,171-,207-,208+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
SungKyunKwan University Curated by ChEMBL					Assay Description Displacement of [125I]exendin-4 from GLP1 receptor in rat RINm5F cells after 2 hrs by gamma counting				J Med Chem 52: 6889-96 (2009) Article DOI: 10.1021/jm901153x BindingDB Entry DOI: 10.7270/Q2RJ4JNM
					More data for this Ligand-Target Pair