BDBM50314313 1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-3-(3,5-dichlorobenzyl)urea::CHEMBL1089681

SMILES: Clc1cc(Cl)cc(CNC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(Br)cc2)c1

InChI Key: InChIKey=JGRNPFVRYKMKOL-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50314313 (1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...) Show SMILES Clc1cc(Cl)cc(CNC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(Br)cc2)c1 Show InChI InChI=1S/C24H28BrCl2N3O/c25-18-5-7-22(8-6-18)30(23-9-11-29(12-10-23)21-3-1-2-4-21)24(31)28-16-17-13-19(26)15-20(27)14-17/h5-8,13-15,21,23H,1-4,9-12,16H2,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant histamine 3 receptor				Bioorg Med Chem Lett 20: 2359-64 (2010) Article DOI: 10.1016/j.bmcl.2010.01.121 BindingDB Entry DOI: 10.7270/Q2Z31ZSM
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50314313 (1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...) Show SMILES Clc1cc(Cl)cc(CNC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(Br)cc2)c1 Show InChI InChI=1S/C24H28BrCl2N3O/c25-18-5-7-22(8-6-18)30(23-9-11-29(12-10-23)21-3-1-2-4-21)24(31)28-16-17-13-19(26)15-20(27)14-17/h5-8,13-15,21,23H,1-4,9-12,16H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG by ion works assay				Bioorg Med Chem Lett 20: 2359-64 (2010) Article DOI: 10.1016/j.bmcl.2010.01.121 BindingDB Entry DOI: 10.7270/Q2Z31ZSM
					More data for this Ligand-Target Pair