BDBM50314314 1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-3-(3,4-dichlorobenzyl)urea::CHEMBL1090024

SMILES: Clc1ccc(CNC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(Br)cc2)cc1Cl

InChI Key: InChIKey=UNUYHVCNCOUDKK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50314314 (1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)-...) Show SMILES Clc1ccc(CNC(=O)N(C2CCN(CC2)C2CCCC2)c2ccc(Br)cc2)cc1Cl Show InChI InChI=1S/C24H28BrCl2N3O/c25-18-6-8-20(9-7-18)30(21-11-13-29(14-12-21)19-3-1-2-4-19)24(31)28-16-17-5-10-22(26)23(27)15-17/h5-10,15,19,21H,1-4,11-14,16H2,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant histamine 3 receptor				Bioorg Med Chem Lett 20: 2359-64 (2010) Article DOI: 10.1016/j.bmcl.2010.01.121 BindingDB Entry DOI: 10.7270/Q2Z31ZSM
					More data for this Ligand-Target Pair