BDBM50314457 (2S)-N-((1S)-2-((2S)-2-(5-fluoro-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide::CHEMBL1090867

SMILES: CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1CCC[C@H]1c1nc(c(F)s1)-c1cccc2ccccc12

InChI Key: InChIKey=WPUCUMPNTFVXFM-RTFZILSDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
X-linked inhibitor of apoptosis protein (XIAP) (Homo sapiens (Human))	BDBM50314457 ((2S)-N-((1S)-2-((2S)-2-(5-fluoro-4-(naphthalen-1-y...) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1CCC[C@H]1c1nc(c(F)s1)-c1cccc2ccccc12 |r| Show InChI InChI=1S/C28H33FN4O3S/c1-17(30-2)26(34)31-23(19-12-15-36-16-13-19)28(35)33-14-6-11-22(33)27-32-24(25(29)37-27)21-10-5-8-18-7-3-4-9-20(18)21/h3-5,7-10,17,19,22-23,30H,6,11-16H2,1-2H3,(H,31,34)/t17-,22-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Antagonist activity at XIAP BIR3 domain by fluorescence polarization assay ... On Thursday, November 10, 2011 9:19 AM from cohen.fred@gene.com: Unfor...				Bioorg Med Chem Lett 20: 2229-33 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.02.021 BindingDB Entry DOI: 10.7270/Q298875B
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 7 (Homo sapiens (Human))	BDBM50314457 ((2S)-N-((1S)-2-((2S)-2-(5-fluoro-4-(naphthalen-1-y...) Show SMILES CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1CCC[C@H]1c1nc(c(F)s1)-c1cccc2ccccc12 |r| Show InChI InChI=1S/C28H33FN4O3S/c1-17(30-2)26(34)31-23(19-12-15-36-16-13-19)28(35)33-14-6-11-22(33)27-32-24(25(29)37-27)21-10-5-8-18-7-3-4-9-20(18)21/h3-5,7-10,17,19,22-23,30H,6,11-16H2,1-2H3,(H,31,34)/t17-,22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Antagonist activity at ML-IAP MLXBIR3SG domain by fluorescence polarization assay ... On Thursday, November 10, 2011 9:19 AM from cohen.fred@gene.com...				Bioorg Med Chem Lett 20: 2229-33 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.02.021 BindingDB Entry DOI: 10.7270/Q298875B
					More data for this Ligand-Target Pair