BDBM50314586 2-(1-Difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)propanoic acid::CHEMBL1092136

SMILES: CC(C(O)=O)c1cccn(C(F)F)c1=O

InChI Key: InChIKey=UBXUMSZRHYSXOA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50314586 (2-(1-Difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)...) Show SMILES CC(C(O)=O)c1cccn(C(F)F)c1=O Show InChI InChI=1S/C9H9F2NO3/c1-5(8(14)15)6-3-2-4-12(7(6)13)9(10)11/h2-5,9H,1H3,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 by enzyme immuno assay				Bioorg Med Chem Lett 20: 2168-73 (2010) Article DOI: 10.1016/j.bmcl.2010.02.040 BindingDB Entry DOI: 10.7270/Q2HT2PGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50314586 (2-(1-Difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)...) Show SMILES CC(C(O)=O)c1cccn(C(F)F)c1=O Show InChI InChI=1S/C9H9F2NO3/c1-5(8(14)15)6-3-2-4-12(7(6)13)9(10)11/h2-5,9H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme immuno assay				Bioorg Med Chem Lett 20: 2168-73 (2010) Article DOI: 10.1016/j.bmcl.2010.02.040 BindingDB Entry DOI: 10.7270/Q2HT2PGV
					More data for this Ligand-Target Pair