BDBM50314589 (1-Difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)acetic acid::CHEMBL1089959

SMILES: OC(=O)Cc1ccn(C(F)F)c(=O)c1

InChI Key: InChIKey=BQSITNTVRUSOMI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50314589 ((1-Difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)ac...) Show SMILES OC(=O)Cc1ccn(C(F)F)c(=O)c1 Show InChI InChI=1S/C8H7F2NO3/c9-8(10)11-2-1-5(3-6(11)12)4-7(13)14/h1-3,8H,4H2,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 by enzyme immuno assay				Bioorg Med Chem Lett 20: 2168-73 (2010) Article DOI: 10.1016/j.bmcl.2010.02.040 BindingDB Entry DOI: 10.7270/Q2HT2PGV
					More data for this Ligand-Target Pair