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SMILES: Clc1ccccc1C(=O)Nc1cccc(c1)-c1nc2sccn2c1-c1ccncc1

InChI Key: InChIKey=AWONUZFYKOTAIK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50315901 (2-chloro-N-(3-(5-(pyridin-4-yl)imidazo[2,1-b]thiaz...) Show SMILES Clc1ccccc1C(=O)Nc1cccc(c1)-c1nc2sccn2c1-c1ccncc1 Show InChI InChI=1S/C23H15ClN4OS/c24-19-7-2-1-6-18(19)22(29)26-17-5-3-4-16(14-17)20-21(15-8-10-25-11-9-15)28-12-13-30-23(28)27-20/h1-14H,(H,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of ErbB2 by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50315901 (2-chloro-N-(3-(5-(pyridin-4-yl)imidazo[2,1-b]thiaz...) Show SMILES Clc1ccccc1C(=O)Nc1cccc(c1)-c1nc2sccn2c1-c1ccncc1 Show InChI InChI=1S/C23H15ClN4OS/c24-19-7-2-1-6-18(19)22(29)26-17-5-3-4-16(14-17)20-21(15-8-10-25-11-9-15)28-12-13-30-23(28)27-20/h1-14H,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair