BDBM50317078 CHEMBL4170656
SMILES: CCc1ccc2cc(CCn3ncc4nc(nc(O)c34)-n3cc(cn3)C(O)=O)ccc2c1
InChI Key: InChIKey=PIKQIBDIDXDIHR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50317078 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50317078
(CHEMBL4170656)Show SMILES CCc1ccc2cc(CCn3ncc4nc(nc(O)c34)-n3cc(cn3)C(O)=O)ccc2c1 Show InChI InChI=1S/C23H20N6O3/c1-2-14-3-5-17-10-15(4-6-16(17)9-14)7-8-28-20-19(12-25-28)26-23(27-21(20)30)29-13-18(11-24-29)22(31)32/h3-6,9-13H,2,7-8H2,1H3,(H,31,32)(H,26,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Cadila Healthcare Limited
Curated by ChEMBL
| Assay Description
Inhibition of PHD2 (unknown origin) |
J Med Chem 61: 6964-6982 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01686
BindingDB Entry DOI: 10.7270/Q2H70JC7 |
More data for this
Ligand-Target Pair | |
Prolyl hydroxylase EGLN3
(Homo sapiens (Human)) | BDBM50317078
(CHEMBL4170656)Show SMILES CCc1ccc2cc(CCn3ncc4nc(nc(O)c34)-n3cc(cn3)C(O)=O)ccc2c1 Show InChI InChI=1S/C23H20N6O3/c1-2-14-3-5-17-10-15(4-6-16(17)9-14)7-8-28-20-19(12-25-28)26-23(27-21(20)30)29-13-18(11-24-29)22(31)32/h3-6,9-13H,2,7-8H2,1H3,(H,31,32)(H,26,27,30) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Cadila Healthcare Limited
Curated by ChEMBL
| Assay Description
Inhibition of PHD3 (unknown origin) |
J Med Chem 61: 6964-6982 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01686
BindingDB Entry DOI: 10.7270/Q2H70JC7 |
More data for this
Ligand-Target Pair | |
Search and Browse
