BDBM50317207 CHEMBL1088517::N-cyclohexyl-2-(7,8-dihydro-4H-isoxazolo[3,4-d]azepin-6(5H)-yl)-N-ethylacetamide

SMILES: CCN(C1CCCCC1)C(=O)CN1CCc2conc2CC1

InChI Key: InChIKey=DKFPJVQUCNQTLS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50317207 (CHEMBL1088517 | N-cyclohexyl-2-(7,8-dihydro-4H-iso...) Show SMILES CCN(C1CCCCC1)C(=O)CN1CCc2conc2CC1 Show InChI InChI=1S/C17H27N3O2/c1-2-20(15-6-4-3-5-7-15)17(21)12-19-10-8-14-13-22-18-16(14)9-11-19/h13,15H,2-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50317207 (CHEMBL1088517 | N-cyclohexyl-2-(7,8-dihydro-4H-iso...) Show SMILES CCN(C1CCCCC1)C(=O)CN1CCc2conc2CC1 Show InChI InChI=1S/C17H27N3O2/c1-2-20(15-6-4-3-5-7-15)17(21)12-19-10-8-14-13-22-18-16(14)9-11-19/h13,15H,2-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair