BDBM50317694 (S)-(2-benzylpyrrolidin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone::CHEMBL1097705

SMILES: O=C(N1CCCN(CC1)C1CCC1)[C@@]1(Cc2ccccc2)CCCN1

InChI Key: InChIKey=ZTGFTYKAQBNXMK-NRFANRHFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50317694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317694 ((S)-(2-benzylpyrrolidin-2-yl)(4-cyclobutyl-1,4-dia...) Show SMILES O=C(N1CCCN(CC1)C1CCC1)[C@@]1(Cc2ccccc2)CCCN1 |r| Show InChI InChI=1S/C21H31N3O/c25-20(24-14-6-13-23(15-16-24)19-9-4-10-19)21(11-5-12-22-21)17-18-7-2-1-3-8-18/h1-3,7-8,19,22H,4-6,9-17H2/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				Bioorg Med Chem Lett 20: 2755-60 (2010) Article DOI: 10.1016/j.bmcl.2010.03.071 BindingDB Entry DOI: 10.7270/Q2Z60P7S
					More data for this Ligand-Target Pair