BDBM50317734 3-methyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1094742

SMILES: Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key: InChIKey=AWHRFIKOWGDBRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50317734 (3-methyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(t...) Show SMILES Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C24H18F3NO2S/c1-15-14-28-23-20(7-4-8-21(23)24(25,26)27)22(15)18-6-3-5-17(13-18)16-9-11-19(12-10-16)31(2,29)30/h3-14H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from LXRalpha ligand binding domain				Bioorg Med Chem Lett 20: 2903-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.031 BindingDB Entry DOI: 10.7270/Q2TD9XJZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50317734 (3-methyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(t...) Show SMILES Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C24H18F3NO2S/c1-15-14-28-23-20(7-4-8-21(23)24(25,26)27)22(15)18-6-3-5-17(13-18)16-9-11-19(12-10-16)31(2,29)30/h3-14H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from LXRbeta ligand binding domain				Bioorg Med Chem Lett 20: 2903-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.031 BindingDB Entry DOI: 10.7270/Q2TD9XJZ
					More data for this Ligand-Target Pair