BDBM50317987 CHEMBL1096072::N-(4-amino-4'-(trifluoromethyl)biphenyl-3-yl)benzamide

SMILES: Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SXNSPGPBTATFRJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50317987 (CHEMBL1096072 | N-(4-amino-4'-(trifluoromethyl)bip...) Show SMILES Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H15F3N2O/c21-20(22,23)16-9-6-13(7-10-16)15-8-11-17(24)18(12-15)25-19(26)14-4-2-1-3-5-14/h1-12H,24H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assay				Bioorg Med Chem Lett 20: 3142-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.091 BindingDB Entry DOI: 10.7270/Q2HX1CT8
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50317987 (CHEMBL1096072 | N-(4-amino-4'-(trifluoromethyl)bip...) Show SMILES Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H15F3N2O/c21-20(22,23)16-9-6-13(7-10-16)15-8-11-17(24)18(12-15)25-19(26)14-4-2-1-3-5-14/h1-12H,24H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assay				Bioorg Med Chem Lett 20: 3142-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.091 BindingDB Entry DOI: 10.7270/Q2HX1CT8
					More data for this Ligand-Target Pair