null

SMILES: OC(=O)C(O)(Cc1cnc2ccccn12)P(O)(O)=O

InChI Key: InChIKey=XZINREBMYQRVSH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50318032 ((+)-2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosp...) Show SMILES OC(=O)C(O)(Cc1cnc2ccccn12)P(O)(O)=O Show InChI InChI=1S/C10H11N2O6P/c13-9(14)10(15,19(16,17)18)5-7-6-11-8-3-1-2-4-12(7)8/h1-4,6,15H,5H2,(H,13,14)(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting				J Med Chem 53: 3454-64 (2010) Checked by Author Article DOI: 10.1021/jm900232u BindingDB Entry DOI: 10.7270/Q21837FJ
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50318032 ((+)-2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosp...) Show SMILES OC(=O)C(O)(Cc1cnc2ccccn12)P(O)(O)=O Show InChI InChI=1S/C10H11N2O6P/c13-9(14)10(15,19(16,17)18)5-7-6-11-8-3-1-2-4-12(7)8/h1-4,6,15H,5H2,(H,13,14)(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting				J Med Chem 53: 3454-64 (2010) Checked by Author Article DOI: 10.1021/jm900232u BindingDB Entry DOI: 10.7270/Q21837FJ
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50318032 ((+)-2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosp...) Show SMILES OC(=O)C(O)(Cc1cnc2ccccn12)P(O)(O)=O Show InChI InChI=1S/C10H11N2O6P/c13-9(14)10(15,19(16,17)18)5-7-6-11-8-3-1-2-4-12(7)8/h1-4,6,15H,5H2,(H,13,14)(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting				J Med Chem 53: 3454-64 (2010) Checked by Author Article DOI: 10.1021/jm900232u BindingDB Entry DOI: 10.7270/Q21837FJ
					More data for this Ligand-Target Pair