BDBM50318196 (Z)-2-(4-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]-quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic Acid::CHEMBL1094809

SMILES: COc1ccccc1C1C2=C(N=c3s\c(=C/c4ccc(OCC(O)=O)cc4)c(=O)n13)c1ccccc1CC2

InChI Key: InChIKey=WIONWZSKKIITNQ-XYGWBWBKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50318196 ((Z)-2-(4-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...) Show SMILES COc1ccccc1C1C2=C(N=c3s\c(=C/c4ccc(OCC(O)=O)cc4)c(=O)n13)c1ccccc1CC2 |c:10,t:12| Show InChI InChI=1S/C30H24N2O5S/c1-36-24-9-5-4-8-22(24)28-23-15-12-19-6-2-3-7-21(19)27(23)31-30-32(28)29(35)25(38-30)16-18-10-13-20(14-11-18)37-17-26(33)34/h2-11,13-14,16,28H,12,15,17H2,1H3,(H,33,34)/b25-16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human Bcl-XL				J Med Chem 53: 3465-79 (2010) Article DOI: 10.1021/jm901004c BindingDB Entry DOI: 10.7270/Q2QF8T11
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