BDBM50318520 1-(isoquinolin-4-yl)-2-methylpent-1-en-3-one oxime::CHEMBL1083793

SMILES: CCC(N=O)C(C)=Cc1cncc2ccccc12

InChI Key: InChIKey=KQZXZRAEAPZDGW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318520 (1-(isoquinolin-4-yl)-2-methylpent-1-en-3-one oxime...) Show SMILES CCC(N=O)C(C)=Cc1cncc2ccccc12 |w:7.7| Show InChI InChI=1S/C15H16N2O/c1-3-15(17-18)11(2)8-13-10-16-9-12-6-4-5-7-14(12)13/h4-10,15H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 channel expressed in CHO cells assessed as inhibition of cinnamaldehyde-induced intracellular calcium influx				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair